Item no.
TRC-V118500-5MG
CAS Number
[918504-65-1]
Unit
5 mg
Molecular formula
C23H18ClF2N3O3S
Molecular weight
489,92
Shipment details
No Dangerous Good
Back to your search result
Description
Category: Aromatics, Heterocycles, Protein Kinase Inhibitors and Activators, Sulfur and Selenium Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White Solid /// Application Notes: Vemurafenib selective BRAFV600E kinase inhibitor, an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. /// References: Halaban, R. et al.: Pigm. Cell. Melonoma Res., 23, 190 (2010)| Yang, H. et al.: Cancer Res., 70, 5518 (2010)| Comin-Anduix, B. et al.: Clin. Cancer Res., 16, 6040 (2010)|
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
Reference Material CoA specimen: for the current lot, please contact your customer service representative at info@labmix24.com
Product data sheet
View all available product details e.g. description, analytes/parameters, CAS Number, concentrations/values, sales unit/product format, method, source, transport information
Quality analytical standards and reference materials for food and environmental analysis, research
Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.