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Description

Category: Carbohydrates and Derivatives, Heterocycles, Isotope Labelled Compounds, Nucleotides, Bases and Related Reagents /// Appearance: White Solid /// Application Notes: Isotope labelled beta-Pseudouridine is an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called ? synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that beta-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. /// References: Ferré-D'Amaré A.R. et al.: Curr. Opin. Struct. Biol., 13, 49 (2003)| Hamma, T. et al.: Chem. Biol., 13, 1125 (2006)| Liang, X.H. et al.: RNA, 8, 237 (2002)| Monobe, M. et al.: Mut. Res. Gen. Toxicol. Env. Mutagen., 538, 93 (2003)|

Structure formula

beta-Pseudouridine-13C, 15N2

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.