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Description

Category: Aromatics, Miscellaneous Reagents /// Application Notes: 1,4-Dimethylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been found in dust particulate matter and is associated with activation of aryl hydrocarbon receptor as a major toxic mode of action in WB-F344 cell line. 1,4-Dimethylnaphthalene has been found to retard the development of epidermoid carcinomas in hamster buccal pouch. 1,4-Dimethylnaphthalene alters the genes associated with the maintenance of a G1/S phase block possibly through the induction of the cell cycle inhibitors KRP1 and KRP2 in potatoes. /// References: Malament, D.S., Shklar, G.: Carcinogenesis, 2, 723 (1981)| Campbell, M.A., et. al.: Fuct. Interg. Genomics, 12, 533 (2012)| Andrysik, Z., et. al.: Mutat. Res-Fund. Mol. M., 714, 53 (2011)

Structure formula

1,4-Dimethylnaphthalene

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.