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MMP-2 Inhibitor III - CAS 704888-90-4 - Calbiochem The MMP-2 Inhibitor III, also referenced under CAS 704888-90-4, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Item no.

SAF-444288-5MG

Unit

1 x 5 mg

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable biphenylsulfonamido-hydroxamate compound that acts a potent and Zn2+-binding site-targeting inhibitor of MMP-2 (IC = 12 nM). It exhibits good selectivity over MMP-9 and MMP-3 (IC = 0.2 and 4.5 microM, respectively) and shows practically no effect towards MMP-1 and MMP-7 (IC >50 microM). Shown to effectively suppress the invasiveness of HT1080 sarcoma cells grown on matrigel.

Structure formula

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