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COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.

Item no.

SAF-236015-5MG

CAS Number

[116686-15-8]

Unit

1 x 5 mg

Molecular formula

C15H13F2NO4S

Molecular weight

341,33

Shipment details

No Dangerous Good

Price on request

Description

A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µ,M in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.

Structure formula

4'-Acetyl-2'-(2,4-Difluorophenoxy)methanesulfonanilide

Analyte	CAS Number	Concentration	Unit	Additional information	Method
4'-Acetyl-2'-(2,4-Difluorophenoxy)methanesulfonanilide	[116686-15-8]

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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