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COX-2 Inhibitor V, FK3311 - CAS 116686-15-8 - Calbiochem The COX-2 Inhibitor V, FK3311, also referenced under CAS 116686-15-8, controls the biological activity of COX-2. This small molecule/inhibitor is primarily used for Cell Signaling applications.

Artikelnr.

SAF-236015-5MG

CAS-Nummer

[116686-15-8]

Einheit

1 x 5 mg

Molekularformel

C15H13F2NO4S

Molekulargewicht

341,33

Transportdaten

No Dangerous Good

Preis auf Anfrage

Beschreibung

A cell-permeable and orally available sulfonanilide that acts as a COX-2-selective non-steroidal anti-inflammatory drug (NSAID). Shown to exhibit 500-fold greater potency in inhibiting the LPS-induced (IC50 = 316 nM in human mononuclear cells) than the non-induced/constitutive (IC50 = 160 µ,M in human platelets) TxB2 production in vitro and effectively alleviate warm ischemia-reperfusion injury in the canine liver and rat lung in vivo.

Strukturformel

4'-Acetyl-2'-(2,4-Difluorophenoxy)methanesulfonanilide

Inhalte

Analyt	CAS-Nummer	Konzentration	Einheit	Zusätzliche Informationen	Methode
4'-Acetyl-2'-(2,4-Difluorophenoxy)methanesulfonanilide	[116686-15-8]

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