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17-DMAG - CAS 467214-21-7 - Calbiochem A potent antitumor analog of 17-AAG that binds to the ATPase site of human Hsp90alpha with high affinity and displays excellent bioavailability and aqueous solubility.

Item no.

SAF-100069-500UG

CAS Number

[467214-21-7]

Unit

Molecular formula

C32H49ClN4O8

Molecular weight

653,21

Price on request

Description

A cell-permeable, water soluble, potent anti-tumor analog of 17-AAG (Cat. No. 100068) that binds to the ATPase site of human Hsp90alpha with high affinity (GI50 = 51 nM for 17-DMAG vs. 120 nM for 17-AAG in the NCI 60-cell panel in vitro activity screen)., A potent antitumor analog of 17-AAG (Cat. No. 100068) that binds to the ATPase site of human Hsp90alpha with high affinity (GI50 = 51 nM for 17-DMAG vs. 120 nM for 17-AAG in the NCI 60-cell panel in vitro activity screen), and displays excellent bioavailability and aqueous solubility.

Structure formula

17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride

Analyte	CAS Number	Concentration	Unit	Additional information	Method
17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride	[467214-21-7]

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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