This Standard Reference Material (SRM) is intended primarily for use as a calibration standard for the measurement of enzymatically released N-linked glycans. Potential applications of SRM 3655 include the benchmarking and comparability of analytical techniques, as a material for ensuring system suitability, and for analytical method validation. This material may also be used to value-assign in-house calibrators or control materials. A unit of NIST-3655 consists of thirteen (13) aqueous solutions of glycans commonly associated with monoclonal antibody therapeutics. Each solution contains a purified free-reducing glycan at a known mass fraction. A unit of NIST-3655 consists of thirteen 0.5 mL vials each containing approximately 0.2 mL of solution, frozen. /// Sample value(s) - please ask for current certificate.
Contents
Analyte
CAS Number
Concentration
Unit
Additional information
Method
G0
37,1 ± 0,4
µg/g
Part A, Cap Color light yellow, Analyte: Glycan Symbol (SNFG Nomenclature)
G0
28,1 ± 0,4
µmol/L
Part A, Cap Color light yellow, Analyte: Glycan Symbol (SNFG Nomenclature)
G0F
40,6 ± 3,7
µg/g
Part B, Cap Color black, Analyte: Glycan Symbol (SNFG Nomenclature)
G0F
27,7 ± 2,5
µmol/L
Part B, Cap Color black, Analyte: Glycan Symbol (SNFG Nomenclature)
G1a
37,7 ± 1
µg/g
Part C, Cap Color red, Analyte: Glycan Symbol (SNFG Nomenclature)
G1a
25,4 ± 0,7
µmol/L
Part C, Cap Color red, Analyte: Glycan Symbol (SNFG Nomenclature)
G1b
35,3 ± 1,3
µg/g
Part D, Cap Color blue, Analyte: Glycan Symbol (SNFG Nomenclature)
G1b
23,8 ± 0,9
µmol/L
Part D, Cap Color blue, Analyte: Glycan Symbol (SNFG Nomenclature)
G1aF
13,1 ± 0,3
µg/g
Part E, Cap Color brown, Analyte: Glycan Symbol (SNFG Nomenclature)
G1aF
8 ± 0,2
µmol/L
Part E, Cap Color brown, Analyte: Glycan Symbol (SNFG Nomenclature)
G2
33,6 ± 1,5
µg/g
Part F, Cap Color pink, Analyte: Glycan Symbol (SNFG Nomenclature)
G2
20,4 ± 0,9
µmol/L
Part F, Cap Color pink, Analyte: Glycan Symbol (SNFG Nomenclature)
G2F
37 ± 4,8
µg/g
Part G, Cap Color dark yellow, Analyte: Glycan Symbol (SNFG Nomenclature)
G2F
20,7 ± 2,7
µmol/L
Part G, Cap Color dark yellow, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S1(6)
31,1 ± 3,3
µg/g
Part H, Cap Color orange, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S1(6)
16,1 ± 1,7
µmol/L
Part H, Cap Color orange, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S2(3)
31,9 ± 2,5
µg/g
Part I, Cap Color light green, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S2(3)
14,3 ± 1,1
µmol/L
Part I, Cap Color light green, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S2(6)
22,7 ± 8,5
µg/g
Part J, Cap Color dark green, Analyte: Glycan Symbol (SNFG Nomenclature)
G2S2(6)
10,2 ± 3,8
µmol/L
Part J, Cap Color dark green, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS1(6)
31,3 ± 2,3
µg/g
Part K, Cap Color purple, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS1(6)
15 ± 1,1
µmol/L
Part K, Cap Color purple, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS2(3)
29,9 ± 1,8
µg/g
Part L, Cap Color clear, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS2(3)
12,6 ± 0,8
µmol/L
Part L, Cap Color clear, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS2(6)
29,3 ± 1,6
µg/g
Part M, Cap Color white, Analyte: Glycan Symbol (SNFG Nomenclature)
G2FS2(6)
12,3 ± 0,7
µmol/L
Part M, Cap Color white, Analyte: Glycan Symbol (SNFG Nomenclature)
Miscellaneous
Certificate of Analysis (specimen)
Reference Material CoA specimen: for the current lot, please contact your customer service representative at info@labmix24.com
Product data sheet
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NIST Standard Reference Materials are used by analytical laboratories in industry, academia and government in order to facilitate commerce and trade and to advance research and development. The SRMs are produced by the engineering laboratory, the material measurement laboratory, and the physical measurement laboratory at NIST. They are available for chemical composition, physical properties, and engineering materials.