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Description

Appearance: Colourless Oil /// Application Notes: (3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(ethoxymethoxy)-cholan-24-oic Acid Methyl Ester is an intermediate in the synthesis of (25R)-3beta,7alpha,12alpha-Trihydroxy-5-cholestenoic Acid (T795130), which is an oxysterol, an oxidized derivatives of cholesterol (C432501), which may be important in many biological processes, including cholesterol homeostasis, atherosclerosis, sphingolipid metabolism, platelet aggregation, apoptosis, and protein prenylation,[1] though their roles are poorly understood. /// References: Schroepfer, G., et al.: Physiol. Rev., 80, 361 (2000)| Bjorkhem, I.: J. Clin. Invest., 6, 725(2002)| Bjorkhem, I., et al.: Arterio. hromb. Vascul. Biol., 22, 734 (2002)

Structure formula

(3alpha,5beta,7alpha,12alpha)-3,7,12-Tris(ethoxymethoxy)-cholan-24-oic Acid Methyl Ester

Contents

Miscellaneous

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.