Item no.
TRC-T796135-10G
CAS Number
[630-22-8]
Unit
10 g
Molecular formula
C5H11NS
Molecular weight
117,21
Shipment details
No Dangerous Good
Back to your search result
Description
Category: Amines, Sulfur and Selenium Compounds /// Appearance: White Solid /// Application Notes: 2,2-Dimethylthiopropionamide is used as a reagent to synthesize Dabrafenib, an inhibitor of BRAF kinase that is used to treat BRAF V600-mutation positive carcinoma. BRAF is a gene that mediates cell growth and is activated by mutations caused by cancer. 2,2-Dimethylthiopropionamide is also used as a reagent to prepare sulfonyl-substituted 4,5-diarylthiazoles, compounds that act as cyclooxygenase-2 inhibitors (anti-inflammatory agents). /// References: Carter, J., et al.: Bioorg. Med. Chem. Lett., 9, 1167 (1999)| Rheault, T., et al.: ACS Med. Chem. Lett., 4, 358 (2013)|
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
Reference Material CoA specimen: for the current lot, please contact your customer service representative at info@labmix24.com
Product data sheet
View all available product details e.g. description, analytes/parameters, CAS Number, concentrations/values, sales unit/product format, method, source, transport information
Quality analytical standards and reference materials for food and environmental analysis, research
Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.