Item no.
TRC-S870002-10MG
Unit
10 mg
Molecular formula
C23H17D6ClN6O2
Molecular weight
456,96
Shipment details
No Dangerous Good
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Description
Category: Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Suvorexant-d6 is the labeled analog of Suvorexant (S870000), a dual (non-selective) orexin receptor antagonist in development by Merck and Co. for the treatment of insomnia. It works by turning off wakefulness rather than by inducing sleep. Users of higher doses had an increased rate of suicidal ideation. /// References: Cox, C., et al.: J. Med. Chem., 53, 5320 (2010)| Baxter, C., et al.: Org. Process Res. Dev., 15, 367 (2011)| Winrow, C., et al.: J. Neurogenet., 25, 52 (2011)| Mieda, M., et al.: CNS Drugs, 27, 83 (2013)| Osborne, R.: Nat. Rev. Drug Discov., 12, 492 (2013)
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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