Item no.
TRC-P218290-10MG
CAS Number
[717906-29-1]
Unit
10 mg
Shipment details
No Dangerous Good
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Description
Category: Amines, Aromatics, Inhibitors, Pfizer compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Gray Solid /// Application Notes: PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats. /// References: Han, et al.: J. Biol. Chem., 284 13193 (2009), Allen, et al.: J. Med. Chem., 53 4332 (2010)
Structure formula
Contents
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