Item no.
TRC-M321252-1MG
CAS Number
[220088-40-4]
Unit
1 mg
Molecular formula
C10H11D3N
Molecular weight
165,25
Shipment details
De Minimis
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Description
Appearance: Clear Colourless Oil /// Application Notes: Metanicotine-d3 is the isotope labelled analog of Metanicotine (M321250), an alkaloid found in the leaves of Duboisia Hopwoodii and a constitutent of tobacco smoke. Also used as a potential drug for the treatment of senile dementia of the Alzheimer's type, and currently being investigated as a nicotinic agonist with CNS selectivity. Metanicotine may have clinical potential due to its high selectivity for CNS nicotinic acetylcholine receptor subtypes relative to peripheral ganglionic and muscle-type nicotinic acetylcholine receptors. /// References: Schmeltz, I., et al.: J. Sci. Food Agric., 15, 744 (1964)| Griffin, W.J. and Luanratana, O.: Phytochemistry, 21, 499 (1982)| Jacob III, P., et al.: J. Chromatogr., 619, 49 (1993)| Lippiello, P.M., et al.: J. Pharm. Exp. Therap., 279, 1422 (1996)
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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