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Description

Category: Diagnostic, Isotope Labelled Compounds, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Clear Colourless to Pale Yellow Oil /// Application Notes: beta-Hydroxyisovaleric Acid-d8 is the isotope labelled analog of beta-Hydroxyisovaleric Acid (H943605), a metabolite of the essential amino acid Leucine. It is synthesized in the human body and studies suggest that beta-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated beta-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency. /// References: Nissen, S. et al.: J. Appl. Physiol., 81, 2095 (1996)| Wilson, G.J. et al.: Nutrit. Metab., 5, 1 (2008)| Mock, D.M. et al.: Am. J. Clin. Nutrit., 76, 1061 (2002)

Structure formula

beta-Hydroxyisovaleric Acid-d8

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.