Item no.
TRC-H942740-0.5MG
Unit
0,5 mg
Shipment details
No Dangerous Good
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Description
Appearance: Light Brown Solid /// Application Notes: 2-Hydroxy Estrone 6-N3-Adenine 2,3-O-Di-t-Butyloxycarbonyl is an intermediate in synthesizing 2-Hydroxy-estrone-6-N3-adenine (90%) (H942165), which is a depurinating adduct that is created by the interaction of specific metabolites of estrogens in the body with DNA. Unfortunately, these adducts are endogenous initiators of various human cancers, such as breast and prostate. /// References: Yang, L., et al.: Prostate, 69, 41 (2009)| Zahid, M., et al.: Chem. Res. Toxicol., 19, 164 (2006)| Zhang, Y., et al.: Metabol. Clin. Exp., 56, 887 (2007)|
Structure formula
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