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Description

Application Notes: 4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride is used as a reagent in the synthesis of amino(thienyl)benzamide derivatives which are used as histone deacetylase inhibitors and have antitumor activity. 4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride is also a reagent in the synthesis of Cefbuperazone (C242540), a second-generation cephalosporin antibiotic. /// References: Hirata, Y., et al.: Bioorg. Med. Chem. Lett., 22, 1926 (2012)| Liu, M., et al.: Zhongguo Yiyao Gongye Zazhi, 41, 649 (2010)| Izumi, K., et al.: J. Chemother., 7 Suppl 4, 173 (1995)

Structure formula

4-Ethyl-2,3-dioxo-1-piperazinecarbonyl Chloride

Contents

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TRC | Toronto Research Chemicals

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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.