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Description

Category: Aromatics, Miscellaneous Reagents /// Appearance: Yellow Oil /// Application Notes: Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate is used in the syntheses of 4-(indol-3-yl)quinazolines as epidermal growth factor receptor tyrosine kinase inhibitors. It is also used to prepare Erlotinib hydrochloride (E625000), a useful drug in treatment of non-small-cell lung cancer. /// References: Lueth, A., et al.: Eur. J. Med. Chem., 43, 1478 (2008)| Barghi, L., et al.: Adv. Pharma. Bull., 2, 119 (2012)

Structure formula

Ethyl 4,5-Bis(2-methoxyethoxy)-2-nitrobenzoate

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.