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Description

Category: Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Very Dark Purple Solid /// Application Notes: 17-DMAG is an analogue of Gelamycin (G304500) and 17-(Allylamino)geldanamycin (A549650). 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG. /// References: Dote, H. et al.: Cancer Res., 66, 9211 (2006)| Smith, V. et al.: Cancer Chemother. Pharmacol., 56, 126 (2005)| Egorin, M.J. et al.: Cancer Chemother. Pharmacol., 49, 7 (2002)|

Structure formula

17-N-(2-Dimethylaminoethylamino)-17-demethoxy Geldanamycin Hydrochloride

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.