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Description

Category: Cross Linking Reagents, Fluorescent Labels and Indicators /// Appearance: Yellow to Dark Yellow Solid /// Application Notes: Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle.Fluorescence: max. Abs. l = 341, max. Em. l = 415 (in water) /// References: Horie, S., et al.: Res. Comm. Chem. Pathol. Pharmacol., 79, 117 (1993) Mayinger, P. & Meyer, D.I.: EMBO J., 12, 659 (1993)| Am. J. Physiol. 262, C803 (1992)| J. Biol. Chem. 266, 13355 (1991).

Structure formula

4,4'-Diisothiocyano-2,2'-stilbenedisulfonic Acid, Disodium Salt

Contents

Miscellaneous

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.