4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile - TRC-D435380-50MG

Description

Application Notes: Kinase inhibitors, such as bosutinib, are useful cancer drugs but their target specificity is not fully understood. 4-[(3,5-Dichloro-4-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile has been employed as a clinical kinase inhibitor bosutinib to elucidate the recognition mechanism between the ATP-binding site and the compound. /// References: Levinson, N. M. and Boxer, S. G., Nat Chem. Biol 10, 127 (2014)| Yen, T. and Beeharry, N., PCT Int. Appl. WO 2013187967 A1 20131219 (2013)

Structure formula

Analyte

CAS Number

Concentration

Unit

Additional information

Method

PF-06651481-00

[1391063-17-4]

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