Item no.
TRC-D242602-2.5MG
Unit
2,5 mg
Shipment details
No Dangerous Good
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Description
Category: Carbohydrates and Derivatives, Isotope Labelled Compounds, Nucleotides, Bases and Related Reagents, Sulfur and Selenium Compounds /// Appearance: White to Off-White Solid /// Application Notes: Labelled 5'-Deoxy-5'-(methylthio)adenosine (D242600). 5?-Deoxy-5?-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5?-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5?-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN). /// References: Pegg, A., et al.: Biochem. J., 115, 241 (1969), Olopade, O., et al.: Cancer Res., 53, 2410 (1993), Hartmann, S., et al.: Clin. Chem., 52, 1127 (2006), Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (2010)
Structure formula
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Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.