Item no.
TRC-C643025-10MG
CAS Number
[168555-66-6]
Unit
10 mg
Molecular formula
C18H19Na2O8P
Molecular weight
440,29
Shipment details
No Dangerous Good /not restricted
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Description
Category: Aromatics, Inhibitors,Pharmaceuticals, Intermediates and Fine Chemicals, Phosphorylating and Phosphitylating Agents /// Appearance: White Solid /// Application Notes: Phosphorylated Combretastatin, a small organic molecule found in the bark of the African bush willow tree Combretum caffrum. Combretastatin-A4 Prodrug Induces Mitotic Catastrophe in Chronic Lymphocytic Leukemia Cell Line Independent of Caspase Activation and Poly(ADP-ribose) Polymerase Cleavage. A potent cytotoxic agent which strongly inhibits the polymerization of tubulin by binding to the colchicine site. /// References: Hamel, E., et al.: Biochem. Pharmacol., 32, 3863 (1983), Chaplin, D.J., et al.: Br. J. Cancer, 74, S86, (1996)
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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