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Description
Category: Aromatics /// Appearance: Off-White Solid /// Application Notes: 4-Chloro-3-(trifluoromethyl)phenyl isocyanate is used as a reagent to synthesize pyrimidinylaminobenzene derivatives, compounds that have antiproliferative activity against melanoma cell lines. 4-Chloro-3-(trifluoromethyl)phenyl isocyanate is also used to synthesize alpha-thymidine analogues that act as antimalarial agents. /// References: Cui, H., et al.: J. Med. Chem., 55, 10948 (2012)| Kim, H., et al.: Bull. Kor. Chem. Soc., 34, 2311 (2013)
Structure formula
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