Item no.
TRC-C292150-10MG
CAS Number
[1797989-42-4]
Unit
10 mg
Shipment details
No Dangerous Good
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Description
Category: Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Beige Solid /// Application Notes: CHIR-99021 is a potent and highly selective inhibitor of glycogen synthase kinase 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells. /// References: Ring, et al.: Diabetes, 52, 588 (2003)| Tighe, et al.: Cell Biol., 8, 34 (2007)| Pan, et al.: Neuropsychopharmacology, 36, 1397 (2011)|
Structure formula
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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.