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Description
Application Note: (2R,3R,4R,5S)-1-Butyl-2-((((2R,3R,4S,5S,6S)-3,4,5-triacetoxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)piperidine-3,4,5-triyl tribenzoate is an intermediate in the synthesis of Miglustat O-beta-D-Glucuronide (M344220), which is a glucuronide derivative of N-Butyldeoxynojirimycin (B691000), an inhibitor of a-glucosidase 1 as well as HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.
Structure formula
-1-butyl-2-((((2r,3r,4s,5s,6s)-3,4,5-triacetoxy-6-(methoxycarbonyl)tetrahydro-2h-pyran-2-yl)oxy)methyl)piperidine-3,4,5-triyl%20tribenzoate.png)
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