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Description
Category: Aromatics /// Appearance: Off-White Solid /// Application Notes: tBHQ is an antioxidant in induction of AP-1, NF-?B, and glutathione S-transferase gene expression. It also disrupts ability of Kelch-like ECH-associated protein 1(Keap1) to target Nrf2, a bZIP transcription factor, for proteasome-mediated degradation and promote nuclear accumulation of Nrf2. /// References: Pinkus, R., et al.: J. Biol. Chem., 271, 13422 (1996)| Zhang, D., et al.: Mol. Cell. Bio., 23, 8137 (2003)
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Structure formula
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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.