Item no.
TRC-B675700-10MG
CAS Number
[179324-69-7]
Unit
10 mg
Molecular formula
C19H25BN4O4
Molecular weight
384,24
Shipment details
No Dangerous Good /not restricted
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Description
Category: Chiral Reagents, Boron Derivatives, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-White Solid /// Application Notes: Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway. /// References: Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005)| Drahl C.: Chem. and Eng. News, 87, 41 (2009)
Structure formula
Contents
Miscellaneous
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