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Description
Application Notes: 2-(Azetidin-1-yl)ethanol is used to prepare novel proline and morpholine derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-hsd-1) for treatment of diabetes and obesity. It is also used in the synthesis of antitumor dibenzonaphthyridine derivatives. /// References: Cheng, H., et al.: PCT Int. Appl. (2005), WO 2005108359 A1 20051117| Gopalsamy, A., et al.: U.S. Pat. Appl. Publ. (2007), US 20070135429 A1 20070614.
Structure formula
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