Item no.
TRC-A549650-25MG
CAS Number
[75747-14-7]
Unit
25 mg
Shipment details
No Dangerous Good
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Description
Category: Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Dark Purple Solid /// Application Notes: Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. /// References: Schnur, R.C., et al.: J. Med. Chem., 38, 3806 (1995), Nimmanapalli, R., et al.: Cancer Res., 61, 1799 (2001), Basso, A.D., et al.: Oncogene, 21, 1159 (2002)
Structure formula
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Contents
Miscellaneous
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Product data sheet
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