Item no.
TRC-A105000-5G
CAS Number
[n/a]
Unit
5 g
Molecular formula
(C14H18N6O)2·H2SO4
Molecular weight
670.74
Shipment details
No Dangerous Good /not restricted
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Description
Category: Inhibitors, Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-White Solid /// Application Notes: Abacavir Sulfate (Abacavir - In House Impurity) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
Hazards
Structure formula
![4-[2-Amino-6-(cyclopropylamino)9H-purin-9yl]-2-cyclopentene-1-methanol sulfate (2:1)](https://labmix24.com/gfx/formula/4-[2-amino-6-(cyclopropylamino)9h-purin-9yl]-2-cyclopentene-1-methanol%20sulfate%20(2:1).png)
Contents
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Product data sheet
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