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Description

Absorbance Maximum: 423nmEmisson Maximum: 540nmSuggested Filters:Excitation: 405/458/488nmEmisson: 480-560nm, Long-term noninvasive cell tracking by fluorescent probes and quantum dots is of great importance to life science and biomedical engineering. Current methods used to fluorescently tag cells have been limited by short signal duration, high background auto-fluorescence or lengthy molecular cloning manipulations using GFP. LuminiCell TrackersBOL> are biocompatible organic fluorescent nanoparticles based on Aggregation Induced Emission technology, termed AIEDots. Aggregation induced emission (AIE) molecules emit fluorescence in an opposite manner than other common fluorophores (Quantum Dots, GFP). Propeller-shaped AIE fluorogens are non-emissive in solutions but become highly fluorescent upon aggregate formation. Due to these differences, LuminiCell TrackersBOL> have very high fluorescence intensities with minimal signal quenching allowing live cell fluorescent tagging for up to 10 days in vitro and 21 days in vivo. These properties make them optimal candidates for long interval live cell bioimaging experiments.

The Luminicell Tracker-540 Vascular Labeling Kit contain green fluorescent AIEDots nanoparticles without TAT sequences. These nanoparticles can be used to fluorescently tag vasculature in living tissues and animals for studies of inflammation and vascular leakage.

Features and Benefits

? Brighter: 10X brighter than other cell labeling technologies
? Photostable: 3X longer fluorescence without signal quenching
? Biocompatible: Non-toxic organic nanoparticles intended for biological applications
? Rapid Protocol: Easy-to-use protocol labels cells within 4 hours