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Description

Human embryonic stem cells (HESC) are pluripotent stem cells that are capable of self-renewal and of differentiation in vitro and in vivo into a wide variety of cell types, including derivatives of all three embryonic germ layers. These primary germ layers will eventually give rise to all the tissues and organs of the body. Mesoderm: bone, cartilage, muscle, blood and vascular system Endoderm: gastrointestinal tract, respiratory tract and endocrine glands (including liver and pancreas) Ectoderm: nervous system, skin CHEMICON(R)'s Human Embryonic Germ Layer Characterization Kit (SCR030) allows researchers to assess the differentiation potential of their HESC to form derivatives of all three embryonic germ layers. Included in the kit are antibodies that are routinely used by stem cell researchers to identify the lineage fates of HESC following either spontaneous or directed differentiation. Mesoderm: Smooth Muscle Actin (CBL171) Cardiac Troponin I (MAB1691-50UG) Endoderm: Alpha Fetoprotein (2004189) Ectoderm: Nestin (ABD69) MAP-2 (MAB3418-50UG)