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Description

Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparan sulfate proteoglycans, entactin/nidogen, and a number of growth factors.QualityMouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testingExtensive PCR testing is performed to screen for a number of pathogensTested and found negative for bacteria, fungi, and mycoplasmaProtein concentrations determined by Lowry methodEndotoxin units measured by Limulus Amoebocyte Lysate assayMatrigel Matrix gel stability is tested for a period of 14 days at 37CBiological activity is determined for each lot using a neurite outgrowth assay.SourceEngelbreth-Holm-Swarm Mouse TumorPreparation and StorageStore at -20C. Avoid multiple freeze-thaws. Do not store in frost-free freezer. KEEP FROZEN.ApplicationCell Growth and DifferentiationMetabolism/Toxicology StudiesInvasion Assaysin vitro and in vivo Angiogenesis Assaysin vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed MiceClick here for Corning Matrigel Lot Selection and Reservation.For Customers in California only: WARNING Please refer to Safety Data Sheet (SDS) Section 15 or Letter in Lieu for more information regarding California Proposition 65.