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Description

A cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked beta sheet aggregates. Associates with aggregated fibrils of synthetic beta/A4-derived peptides beta(1-28) and beta(1-40), resulting in a shift in the excitation maximum and an enhanced emission. Excitation max.: ~385 nm (free), ~437 nm (bound), emission max.: ~445 nm (free), ~485 nm (bound)., A cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils. Useful in monitoring stacked beta sheet aggregates.