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Description

A tetrapeptidyl hydroxamic acid that inhibits interstitial and granulocyte collagenases (MMP-1 and MMP-8, IC50 = 1 µ,M), granulocyte gelatinase (MMP-9, IC50 = 30 µ,M), adn skin fibroblast stromelysin (MMP-3, IC50 = 150 µ,M). Retains its activity even after prolonged incubation with PRONASE Protease (Cat. No. 53702) or human neutrophil elastase., A tetrapeptidyl hydroxamic acid that inhibits MMP-1 and MMP-8 (IC50 = 1.0 µ,M), MMP-9 (IC50 = 30 µ,M) and MMP-3 (IC50 = 150 µ,M). Retains its activity even after prolonged incubation with PRONASE Protease (Cat. Nos. 53702 or 537088) or human granulocyte elastase.