Item no.
SAF-217694-10MG
CAS Number
[93718-83-3]
Unit
1 x 10 mg
Molecular formula
C14H14O4S2
Molecular weight
310,39
Shipment details
No Dangerous Good /not restricted
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Description
A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki = 32 nM, 96 nM, and 40 nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50 = 1.8 µ,M). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments.
Structure formula
Contents
Miscellaneous
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