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Description
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Pale Yellow Solid /// Application Notes: Human respiratory syncytial virus (HRSV) is a major respiratory viral pathogen causing moderate to severe upper and lower respiratory tract infections in all ages and across a wide range of patient populations. VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms by binding into a small hydrophobic cavity in the inner core of F protein, interacting simultaneously with both the HR1 and HR2 domains. /// References: Andries, K., et al.: Antiviral Res., 60, 209 (2003), Douglas, J., et al.: J. Virol., 77, 5054 (2003), Cianci, C., et al.: Antimicrob. Agents Chemother., 48, 413 (2004)
Structure formula

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Quality analytical standards and reference materials for food and environmental analysis, research
Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.