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TRC-T774245-10MG
Item no.
TRC-T774245-10MG
CAS Number
[35943-35-2]
Unit
10 mg
Molecular formula
C13H16N6O4
Molecular weight
320,30 (anhydrous basis)
Shipment details
No Dangerous Good /not restricted

Description

Category: Anti-virals, Aromatics, Heterocycles, Inhibitors, Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White Solid /// Application Notes: Triciribine is an antitumor tricyclic nucleoside. Triciribine acts as a potent, small-molecule inhibitor of AKT phosphorylation in subjects with solid tumors contining activated AKT. Triciribine is also a selective inhibitor of HIV-1 and HIV-2, including strains known to be resistant to AZT or TIBO. /// References: Garrett, C.R. et al.: Invest. New Drugs, 29, 1381 (2011)| Ptak, R.G. et al.: AIDS Res. Human Retrovir., 14, 1315 (1998)| Bennett, L.L. et al.: BIochem. Pharmacol., 27, 233 (1978)|

Structure formula

Triciribine hydrate

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.