Item no.
TRC-T548700-25MG
CAS Number
[1222998-36-8]
Unit
25 mg
Molecular formula
C35H28F3N5O2
Molecular weight
607,62
Shipment details
No Dangerous Good
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Description
Category: Amines, Aromatics, Heterocycles, Pfizer Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-Wite Solid /// Application Notes: Torin 1 is a potent and selective mTOR inhibitor (IC50 = 2 - 10 nM for mTORC1 and mTORC2). Displays 200-fold selectivity for mTOR over DNA-PK, ATM and hVps34. /// References: Thoreen, et al.: J. Biol. Chem., 284, 8023 (2009), Liu, et al.: J. Med. Chem., 53, 7146 (2010), Peterson, et al.: Peterson, et al.: Cell, 146 408 (2011)
Structure formula
Contents
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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Quality analytical standards and reference materials for food and environmental analysis, research
Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.