Item no.
TRC-T445100-1MG
CAS Number
[420849-22-5]
Unit
1 mg
Molecular formula
C11H7NOS
Molecular weight
201,24
Shipment details
No Dangerous Good /not restricted
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Description
Category: Inhibitors /// Appearance: Dark Brownish Blue Solid /// Application Notes: A cell permeable, potent PARP inhibitor with an IC50 of 450nM. Shown to be neuroprotective against oxygen-glucose deprivation injury in vitro in cultured murine cortical cells ( IC50 of 150nM) and in vivi in rat transient focal ischemia model (3 mg/kg ip). /// References: Chiarugi, A., et al.: J. Pharmacol. Exp. Ther., 305, 43 (2003), pellicciari, R., et al.: Farmaco., 58, 851 (2003)
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