Item no.
TRC-T338200-10MG
CAS Number
[918633-87-1]
Unit
10 mg
Molecular formula
C9H16Br2N5O4P
Molecular weight
449,04
Shipment details
No Dangerous Good
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Description
Category: Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Yellow Solid /// Application Notes: TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell /// References: Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012)| Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012)| Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012)|
Structure formula
Contents
Miscellaneous
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