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Description

Category: Aromatics /// Appearance: Yellow Solid /// Application Notes: Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants. /// References: Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980)| Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982)| Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983)| Li, S. et al.: J. Asian Nat. Prod. Res., 8, 281 (2006)| Shi, Y.Q. et al.: Anticancer. Res., 21, 2847 (2001)|

Structure formula

Rhein 8-Glucoside

Contents

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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.