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Description

Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals, Tyrosine Kinase Inhibitors /// Appearance: Yellow Solid /// Application Notes: A flavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. /// References: Graziani, Y. et al.: J. Biochem., 135, 583 (1983)| Levy, J. et al.: Biochem. Biophys. Res. Comm., 123, 1227 (1984)| Wei, Y.Q. et al.: Cancer Res., 54, 4952 (1994)|