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TRC-P839643-2.5MG
Item no.
TRC-P839643-2.5MG
CAS Number
[1190307-88-0]/unlabelled
Unit
2,5 mg
Molecular formula
C22H24D5FN3O9P
Molecular weight
534,48
Shipment details
No Dangerous Good

Description

Category: Aromatics, Anti-virals, Amines, Heterocycles, Isotope Labelled Compounds, Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: PSI-7977-D5 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-alpha-fluoro-beta-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. /// References: Lam, A.M.,et al.: Antimicrob. Agents. Chemotherapy., 56, 3359 (2012)| Lam, A.M., et al.: J. Virol., 85, 12334 (2011)| Sofia, M.J., et al.: J. Medn. Chem., 53, 7202 (2010)|

Structure formula

PSI-7977-D5

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.