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Description

Category: Amines, Aromatics, Chiral Reagents, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: L-Propoxyphene-d5 Hydrochloride is the isotope labelled analog and L-isomer of Propoxyphene Hydrochloride (P831500), a controlled substance (opiate) and analgesic (narcotic). The alpha-DL-and D-diastereoisomers possess marked analgesic activity in contrast to the beta-diastereoisomers which are substantially inactive. Oral administration of L-Propoxyphene Hydrochloride enhances the analgesic activity of D-Propoxyphene Hydrochloride. /// References: Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971)| McEwan, B., et al.: Anal. Profiles Drug Subs., 1, 301 (1972)| Murphy, P.J., et al.: J. Pharmacol. Exp. Ther., 199, 415 (1976)

Structure formula

L-Propoxyphene-d5 Hydrochloride

Contents

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TRC | Toronto Research Chemicals

Quality analytical standards and reference materials for food and environmental analysis, research

Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.