Item no.
TRC-P580500-50MG
CAS Number
[110078-46-1]
Unit
50 mg
Molecular formula
C28H54N8
Molecular weight
502.78
Shipment details
No Dangerous Good
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Description
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Pale Beige Solid /// Application Notes: Plerixafor is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-alpha (SDF-1-alpha). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). /// References: Xie, T., et al.: Science, 290, 328 (2000), Leone, D., et al.: J. Pharmacol. Exp. Ther., 305, 1150 (2003)
Structure formula
Contents
Miscellaneous
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