Item no.
TRC-O293977-2.5MG
Unit
2,5 mg
Molecular formula
C913C5H24O3
Molecular weight
245,3
Shipment details
to be checked
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Description
Application Note: 4-Octyl Itaconate-13C5, is a labeled analogue of 4-Octyl Itaconate, which increases nuclear factor erythroid 2-related factor 2 (Nrf2) protein levels and expression of Nrf2 target genes and enhances LPS-induced Nrf2 stabilization in mouse macrophages. In vivo, 4-octyl itaconate (50 mg/kg) decreases serum levels of IL-1beta and TNF-alpha, increases Nrf2 protein expression, and protects against LPS-induced lethality in wild-type, but not Nrf2 knockout, mice.
Structure formula
Contents
Miscellaneous
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Product data sheet
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Founded in 1982, Toronto Research Chemicals is specialized in the development and production of reference materials used in research as well as food safety testing and environmental analysis. The range of more than 350,000 products includes reference standards for pesticides and metabolites, impurities, natural compounds and complex organic small molecules not otherwise commercially available.