Item no.
TRC-N900200-5MG
CAS Number
[204326-43-2]
Unit
5 mg
Molecular formula
C9H5BrN2O3
Molecular weight
269,05
Shipment details
No Dangerous Good
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Description
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White Solid /// Application Notes: NS-2028 potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). NS-2028 blocks sGC activity in murine cerebellum induced by S-nitroso-glutathione and NMDA. NS-2028 inhibits VEGF-induced cGMP accumulation, abolishes VEGF-induced migration in postcapillary venular endothelial cells (CVEC). /// References: Olesen, et al.: Br. J. Pharmacol., 123, 299 (1998), von Wantoch Rekowski, et al.: Bioorg. Med. Chem. 18, 1288 (2010)
Structure formula
Contents
Miscellaneous
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