4-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanone - TRC-M325752-50MG

Description

Category: Heterocycles, Isotope Labelled Compounds, Mutagenesis Research Chemicals, Nicotine Derivatives, /// Appearance: Off-White to Beige Solid /// Application Notes: Labelled NNK (M325750). This compound was present in the highest concentrations in smokeless tobacco out of the nitrosamines identified. It is likely to be important in the etiology of cancers of the lung, oral cavity, and pancreas in people who use tabacco products. Readily produces cancer in rats and hamsters. Carcinogen. /// References: Koenigs, L., et al.: Drug Metab. Dispos., 25, 1407 (1997), Gu, J., et al.: Toxicol. Appl. Pharmacol., 165, 158 (2000), Jalas, J., et al.: Chem. Res. Toxicol., 18, 95 (2005), Zhu, L., et al.: Drug Metab. Dispos., 34, 1672(2006)

Structure formula

4-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanone

Contents

Analyte

CAS Number

Concentration

Unit

Additional information

Method

4-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanone

[86270-92-0]

Miscellaneous

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