Item no.
TRC-L378050-25MG
CAS Number
[n/a]
Unit
25 mg
Molecular formula
C16H14I4N2O3
Molecular weight
789.91
Shipment details
No Dangerous Good
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Description
Category: Amines, Aromatics, Chiral Reagents, Impurities /// Appearance: Beige Solid /// Application Notes: Levothyroxine N-Methylamide is an impurity of Thyroxine (T425600), one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia. /// References: Post, A., et al.: Anal. Profiles Drug Subs., 5, 225 (1976)| Nelson, J.C., et al.: Clin. Chem., 34, 1737 (1988)| Fischer, D.A., et al.: Clin. Chem., 42, 135 (1996)| Cavalieri, R.R., et al.: Thyroid, 7, 177 (1997)
Structure formula
Contents
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